Finde ich toll, dass die Conversionrate von Beta-Carotin in Vitamin A jetzt gesetzlich festgelegt ist- dies muss nur noch mein Genom merken sonst bekomme ich evt. noch ein Ordnungswidrigkeitsverfahren auferlegt
Ich bin de fakto einer dieser Nonresponder, was gar nicht mal so ungewöhnlich ist:
Healthy American Women & Men (45 Percent) Did Not Convert Beta Carotene
Lin Y, et al. Variability of the conversion of beta-carotene to vitamin A in women measured by using a double-tracer study design. American Journal of Clinical Nutrition 2000 Jun;71(6):1545- 54.
Comment: Lin’s study of 11 healthy well-fed women living in a controlled environment found that 5 out of 11 of them (45%) did not experience measurable increases in their blood vitamin A after consuming beta-carotene. The authors said, “The vitamin A activity of ß-carotene is variable and surprisingly low in women. The reasons for this are not well understood. The vitamin A activity of ß-carotene in men is still uncertain.”
Hickenbottom SJ, et al. Variability in conversion of ß-carotene to vitamin A in men as measured by using a double-tracer study design. American Journal of Clinical Nutrition 2002 May:75(5): 900-907.
Comment: This study evaluated the vitamin A activity of beta-carotene in 11 healthy, well-fed men living in a controlled environment and found similar results as was seen in the Lin study. Five of the eleven men (45%) did not experience increased vitamin A blood levels after betacarotene consumption. The authors concluded, “Vitamin A activity of beta-carotene, even when measured under controlled conditions, can be surprisingly low and variable.”
Nierenberg DW, et al. Effects of 4 y of oral supplementation with beta-carotene on serum concentrations of retinol, tocopherol, and five carotenoids. American Journal of Clinical Nutrition 1997 Aug;66(2):315-319.
Comment: Nierenberg’s four-year study of high dose (41,000 IU per day) beta-carotene supplementation with a variety of people showed a 151% average increase in blood betacarotene levels, but no significant increase in blood vitamin A.
Übrigens: Die Conversionrate bei Respondern ist auch um so schlechter je schlechter die Schilddrüse arbeitet.