"Weiss jemand, welche Bestandteile des Corona-Virus die Nebenniere angreift und schädigt ? Und wie dieser schädigende Angriff im einzelnen abläuft ? "
Diese Frage kann ich dir nicht im Detail beantworten. Aber aus dieser Studie bezüglich Nebenniereschwäche und Sars-Cov-2 Infektion geht hervor, dass die untersuchten Gewebeproben von an/mit Sars-Cov-2 Verstorbenen aus dem Zeitraum März 2020 - März 2021 stammen (also mit hoher Wahrscheinlichkeit ungeimpft verstorben), sowie aus Januar 2012 - Februar 2020 für die nicht Covid-19 infizierte Kontrollgruppe.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601687/
We performed a comprehensive histopathological examination of adrenal tissue sections from autopsies of patients that died due to COVID-19 (40 cases), collected from three different pathology centres in Regensburg, Dresden, and Zurich (appendix pp 1–3). We observed evidence of cellular damage and frequently small vessel vasculitis (endotheliitis) in the periadrenal fat tissue (six cases with low and 13 cases with high density; appendix p 10) and much milder occurrence in adrenal parenchyma (ten cases with low and one case with moderate score; appendix p 10), but no evidence of thrombi formation was found (appendix p 10). Endotheliitis has been scored according to a semi-quantitative immunohistochemistry analysis as described in the appendix (p 4). Additionally, in the majority of cases (38 cases), we noticed enhanced perivascular lymphoplasmacellular infiltration of different density and sporadically a mild extravasation of erythrocytes (appendix p 10). However, no evidence of widespread haemorrhages and degradation of adrenocortical cells were found, which is consistent with histological findings reported previously.5 In another autopsy study analysing adrenal glands of patients with COVID-19, additional signs of acute fibrinoid necrosis of small vessels in adrenal parenchyma, subendothelial vacuolisation and apoptotic debris were found.5
Adrenal gland is frequently targeted by bacteria and viruses, including SARS-CoV,10 which was responsible for the 2002–04 outbreak of SARS in Asia. Considering that SARS-CoV-2 shares cellular receptors with SARS-CoV, including angiotensin-converting enzyme 2 and transmembrane protease serine subtype 2, its tropism to the adrenal gland is therefore conceivable.
